Abstract: In order to grasp the resistance characteristics of gas-liquid two-phase flow in stick venturi scrubbers, based on the multiphase flow theory, a three-dimensional CFD model was established. The impacts of stick spacing, air flow and liquid-gas ratio on the pressure loss were studied, and a resistance characteristic model was established. The relationship among stick spacing, air flow and liquid-gas ratio was obtained based on the resistance characteristic model. The results show that the pressure loss between the venturi bar layer and the lower cylinder increases in power exponent with the decrease of stick spacing and the increase of air flow, and it increases in linear with the increase of liquid-gas ratio. The pressure loss of the upper cylinder increases in quadratic with the increase of air flow. The max error between the resistance characteristic model and experimental data is 16. 88%, which verifies the model effectiveness.