Abstract: The plastic criterion popularly used in slope stability analysis is the Mohr-Coulomb criterion.A formula based on the basic principles of the Hoek-Brown failure criterion and the Morgenstern-Price scheme was deduced.The disadvantage that data are empirically obtained in slope stability analysis is overcome by adopting this method and the computing results are more accurate and reasonable.An example was discussed to compare the slope stabilities with different failure criteria,and the stability analysis of Anjialing open-pit mine slope was carried out by using the Morgenstern-Price scheme based on the Hoek-Brown criterion.